补充外源性抗氧化剂对运动诱导的适应性变化的影响
Effects of Exogenous Antioxidants Supplementation on Exercise-induced Adaptive Changes
  
DOI:10.12064/ssr.20200409
中文关键词:自由基  氧化应激  外源性抗氧化剂  运动诱导
英文关键词:free radicals  oxidative stress  exogenous antioxidants  exercise-induced
基金项目:国家自然科学基金(81771500)。
作者单位
潘善瑶 苏州大学 体育学院江苏 苏州 215021 
罗 丽 苏州大学 体育学院江苏 苏州 215021 
王国祥 苏州大学 体育学院江苏 苏州 215021 
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中文摘要:
      采用文献资料法对补充外源性抗氧化剂对运动诱导的适应性变化的影响进行探讨。研究发现为了抵抗自由基的消极作用,运动爱好者常摄取外源性抗氧化剂来消除运动时产生的自由基。抗氧化剂的补充对运动带来的适应性变化有抑制作用,这可能是由于内源性细胞氧化还原状态的调节依赖于机体中复杂的自由基产生和消除系统,这些系统可以精确地调节特定的自由基。而常用的抗氧化剂不具备特异性消除自由基的能力,反而破坏了机体这些系统的调节能力,不仅消除了有害的活性氧/活性氮(ROS/RNS),还影响了细胞适应所需的相关信号。但以往研究在探讨运动或抗氧化剂对于机体氧化还原状态的影响时,没有将氧化还原状态的个体差异考虑在内。ROS/RNS浓度对运动训练适应性和运动表现具有非线性作用,运动时产生适量ROS/RNS有利于机体对运动产生良好的适应性变化,当运动时产生的ROS/RNS未达到对机体有害的浓度范围时,外源性抗氧化剂的补充可能会影响细胞适应所需的ROS / RNS相关信号,抑制机体对运动产生适应性变化。
英文摘要:
      This paper aims to investigate the effects of supplemental exogenous antioxidants on exercise-induced adaptive changes based on the method of literature review. It is found that in order to resist the negative effects of free radicals, sports enthusiasts often take in exogenous antioxidants to eliminate free radicals generated during exercise. The reason why antioxidant supplementation has an inhibitory effect on adaptive changes induced by exercise is that the regulation of endogenous cellular redox status depends on complex free radical production and elimination systems in the body, which can precisely regulate specific free radicals. However, the commonly used antioxidants do not have the specific ability to eliminate free radicals, but instead destroy the regulatory ability of these systems in the body, thus eliminating harmful reactive oxygen species/reactive nitrogen species (ROS/RNS), and affecting the relevant signals required for cell adaptation. However, individual differences in redox status have not been taken into account in previous studies on the effects of exercise or antioxidants on redox status. The concentration of ROS / RNS has a non-linear effect on exercise adaptability and performance. The proper amount of ROS/RNS generated during exercise is conducive to the body's adaptability to exercise. When ROS / RNS generated during exercise does not reach the concentration range harmful to the body, the supplement of exogenous antioxidants may affect the ROS / RNS related signals required for cell adaptation and hereby inhibit the adaptive changes of the body to exercise.
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