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运动与应激:线粒体与内质网的相互作用 |
Exercise and stress response: interaction between mitochondria and endoplasmic reticulum |
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DOI: |
中文关键词:内质网 线粒体 Ca2+稳态 凋亡 自噬 运动 |
英文关键词:endoplasmic reticulum mitochondrion Ca2+ homeostasis apoptosis autophagy exercise |
基金项目:国家自然科学基金(31171142) |
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中文摘要: |
线粒体和内质网在细胞活动中扮演着不同的角色。然而研究发现这两种细胞器在结构和功能上均有所联系,这为细胞器间的物质传递、维持细胞内钙稳态以及调节细胞凋亡和自噬提供了基础。 |
英文摘要: |
Mitochondria and endoplasmic reticulum play different roles in cellular activities. However, recent studies suggest that they interact on each other both structurally and functionally, which provides a basis for substrate transport between organelles, maintaining intracellular Ca2+ homeostasis as well as regulating cellular apoptosis and autophagy. |
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