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| 上海市青少年运动员ACTN3 R577X基因多态性与爆发力素质及其表型指标的关联研究 |
| Correlation of ACTN3 R577X Polymorphism with Power Quality and Related Phenotype Indexes of Shanghai Adolescent Athletes |
| Received:March 01, 2017 |
| DOI： |
| 中文关键词:青少年运动员 ACTN3 基因 多态性 爆发力素质 表型 |
| 英文关键词:adolescent athlete ACTN3 gene polymorphism power quality phenotype |
| 基金项目:上海市体育局科技雏鹰计划项目（14CY003） |
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| 中文摘要: |
| 目的：探讨ACTN3 R577X多态性与青少年运动员爆发力素质及其表型指标的关联性，并检验ACTN3 R577X作为分子标记在青少年运动员科学选材中应用的可行性。方法：选取上海地区青少年业余体校青少年运动员96名，其中男运动员58名，女运动员38名，根据项目特点分为爆发力组和耐力组；利用SNaPshot SNP分型技术对采集的DNA样本进行基因分型。爆发力组运动员进行立定跳远、原地纵跳指标的测试。结果：青少年爆发力组运动员ACTN3 R577X基因型分布与青少年耐力组运动员(x2=7.289，P<0.05)和对照组人群(x2=6.831，P<0.05)均存在显著性差异；青少年爆发力组运动员的ACTN3 R577X等位基因频率与青少年耐力组运动员(x2=7.498，P<0.01)和对照组人群(x2=7.923，P<0.01)均存在显著性差异。在青少年爆发力组男、女运动员中，RR、RX基因型运动员的立定跳远和原地纵跳成绩都要显著性高于XX基因型的运动员（P<0.05，P<0.01）。结论 ACTN3基因 R577X多态性与上海地区青少年运动员爆发力素质存在关联，ACTN3基因 R577X多态性与立定跳远、原地纵跳等爆发力素质表型指标存在关联，ACTN3 基因R577X多态性可以作为青少年速度力量型运动员选材的分子标记。 |
| 英文摘要: |
| Objective: This study explores the correlation of ACTN3 R577X polymorphism with adolescent athletes' power quality and phenotype indexes and examines the practicability of using ACTN3 R577X as a molecular marker in talent identification. Method: 96 adolescent athletes from Shanghai amateur sports schools, 58 male and 38 female, were grouped into power group and endurance group according to the characteristics of their sports. SNaPshot was used for the genotype of the collected athletes' DNA. The indices of standing long jump and standing vertical jump of the power group athletes were measured. Result: There is a significant difference between the ACTN3 R577X genotype distribution of the power group and those of the endurance group (x2=7.289, P<0.05) and control group (x2=6.831, P<0.05). And there is also a significant difference between the ACTN3 R577X allele frequency of the power group and those of the endurance group(x2=7.498, P<0.01) and control group (x2=7.923, P<0.01). In the power group of both the male and female athletes, the results of standing long jump and standing vertical jump of RR and Rx genotype athletes are much better than those of the XX genotype athletes (P<0.05, P<0.01). Conclusion: ACTN3 R577X is closely correlated with the power quality of Shanghai junior athletes. It also correlates with phenotype indexes of power such as standing long jump and standing vertical jump. ACTN3 R577X may be used as a molecular marker in selecting junior speed-strength-type athletes. |
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