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| 低氧环境、运动训练对红细胞免疫功能影响的研究进展 |
| Research Progress on the Effects of Exercise Training on Erythrocyte Immunologic Function in Low Oxygen Environment |
| Received:November 29, 2018 |
| DOI： |
| 中文关键词:低氧 运动 红细胞免疫 |
| 英文关键词:hypoxia exercise erythrocyte immunity |
| 基金项目:上海市体育局科研攻关与科技服务课题（18JT004） |
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| 中文摘要: |
| 红细胞生物学领域研究正在经历一场悄无声息的变革。长期以来，红细胞被认为是氧气的载体，现在正逐渐成为天然免疫反应的重要调节剂。红细胞结合并清除血循环中的趋化因子和病原体，同时根据环境的不同，红细胞可以促进免疫激活，也可以维持免疫静止。低氧训练一直是运动科学研究领域的热点，越来越多的研究发现，在低氧训练过程中运动员疾病易感性增加，免疫力发生改变，作为天然免疫重要组成部分的红细胞免疫如何改变值得探讨，究竟低氧坏境、运动训练与红细胞免疫之间有着怎样的联系。文章采用文献综述的方法，对国内外低氧、运动与红细胞免疫的研究进行总结与分析，为今后的研究提供理论参考。 |
| 英文摘要: |
| Research in the field of erythrocyte biology is undergoing a quiet transformation. Red blood cells have long been recognized as carriers of oxygen and are now becoming important regulators of innate immune responses. Red blood cells bond and remove chemokines and pathogens in the blood circulation. At the same time, depending on the environment, red blood cells can promote immune activation and maintain immune quiescence. Hypoxia training has always been a hot topic in the field of sports science research. More and more studies have found that athletes' disease susceptibility increases and immunity changes during hypoxia training. Red blood cells are an important component of innate immunity. It is worth discussing about how to change erythrocyte immunity and what is the connection among hypoxic conditions, exercise training and red erythrocyte immunity. This paper summarizes and analyzes the research on hypoxia, exercise and erythrocyte immunity at home and abroad by means of literature review, which provides a theoretical reference for future research. |
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