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| 骨关节炎机制及营养防治的研究进展 |
| Research Progress of Nutrition in Prevention and Treatment of Osteoarthritis |
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| DOI：10.12064/ssr.2021032201 |
| 中文关键词:骨关节炎 发病机制 营养 治疗 |
| 英文关键词:osteoarthritis pathogenesis nutrition treatment |
| 基金项目:上海自然科学基金(19ZR1452900)；科技部重点研发项目(2020YFC2005604)；国家自然基金面上项目(31371197) |
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| 中文摘要: |
| 骨关节炎(osteoarthritis，OA)是一种较常见的慢性关节疾病。OA病理基础是关节软骨病变，发病机制繁杂，主要症状为关节疼痛和活动受限。近年来关于OA的机制和治疗指南不断更新，其中营养物质对OA的治疗有独特而重要的作用。本文旨在阐述OA潜在的发病机制及现阶段营养治疗进展，为OA的预防和治疗提供参考。 |
| 英文摘要: |
| Osteoarthritis (OA) is a common chronic joint disease characterized by pathological changes of articular cartilage and subchondral bone, and osteophyte formation at the edge of joint. The pathological basis of OA is articular cartilage disease, the pathogenesis is complex, the main symptoms are pain and inflexibility. The mechanism and treatment guidelines of OA are constantly updated in recent years, in which nutrients play a unique and important role in the treatment of OA. The purpose of this paper is to elaborate the potential pathogenesis of OA and progress of nutritional therapy at this stage, and to provide reference for the prevention and treatment of osteoarthritis. |
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